Qualigenix bills fertility and IVF care for REI practices, IVF centers and embryology labs. We sort covered services from self-pay ones before treatment starts, bill the covered portion to the plan or fertility benefit manager with the right codes, and keep self-pay packages, deposits and refunds reconciled.
Fertility billing works in two tracks. Covered services, such as the infertility workup, some monitoring and procedures a plan or fertility benefit manager has authorized, are coded and billed to the payer. Services the plan excludes are priced up front, with a Good Faith Estimate for self-pay patients, and collected as packages or deposits. Qualigenix runs both tracks for fertility programs in 48 states with 98.9% coding accuracy. Call 786-259-0231 to talk through your payer mix with a specialist.
The diagnosis code often decides whether a plan pays. Infertility diagnoses (N97.x for female, N46.x for male) support the workup and treatment a plan covers, while Z31.x codes describe encounters for procreative management such as fertility testing, counseling and preservation. Embryology lab work has its own CPT range (89250–89356), and each step, from culture and ICSI to biopsy, cryopreservation and storage, is billed separately where the plan covers it.
Many employers carve fertility benefits out of the medical plan and hand them to a fertility benefit manager such as Progyny, Carrot or WINFertility. Each one has its own authorization process, cycle definitions and claim rules, and some programs reimburse the patient instead of paying the clinic. A cycle started under the wrong authorization, or billed to the medical carrier when the benefit sits with the manager, comes back unpaid.
Some commercial payers pay IVF as a case rate using HCPCS S-codes, such as S4011 for in vitro fertilization, S4015 for a complete IVF cycle, S4035 for a stimulated IUI cycle and S4042 for management of ovulation induction. Medicare does not recognize S-codes, and payers that do use them differ on what each case rate includes. Bill the case rate and the itemized CPT codes for the same cycle and the claim is denied as a duplicate. Bill itemized codes when the contract pays a case rate and the claim pays the wrong amount.
For many patients, most of a cycle is self-pay. Clinics sell multi-cycle packages, shared-risk or refund programs, and financed plans, and each creates deposits, partial refunds and credits that have to be tied back to the right patient and cycle. When those balances aren't reconciled, the clinic either owes refunds it hasn't tracked or carries credits it can't apply.
Fertility benefits come with limits that standard eligibility checks don't return: lifetime dollar maximums, cycle counts, age limits, and a requirement for a documented infertility diagnosis before treatment. State mandates differ on whether they require coverage for diagnosis only, IUI, or IVF, and self-funded employer plans may not follow the state mandate at all.
Plans approve treatment based on their own definition of infertility, usually a period of unsuccessful attempts that varies with age, plus test results such as AMH and FSH, imaging of the uterus and tubes, and a semen analysis for the partner. Cycle records need to show stimulation, monitoring and retrieval dates so each billed service maps to an authorized cycle.
Under the No Surprises Act, uninsured patients and patients who choose not to use their insurance must receive a Good Faith Estimate when they schedule care or ask for one. If the final bill is at least $400 more than the estimate, the patient can use the federal patient-provider dispute resolution process. Fertility clinics with large self-pay volumes need an estimate workflow that matches what they eventually bill.
Each gap above maps to a step in how Qualigenix verifies, codes and collects fertility revenue.
Certified coders (CPC and CCS) code each visit, procedure and lab step with the diagnosis that matches the patient's coverage, from the first workup to embryo transfer and storage. Across all Qualigenix clients, coding accuracy is 98.9%.
We identify whether the fertility benefit sits with the medical carrier or a fertility benefit manager, submit cycle authorizations in that payer's format, and track the authorized cycle dates so monitoring and procedures are billed inside them.
We read each payer contract to see whether it pays IVF as an S-code case rate or itemized CPT, and we bill to the contract. Case-rate and itemized lines never go out together for the same cycle.
We prepare self-pay estimates, post deposits and package payments to the right patient and cycle, and reconcile refund-program balances so your team knows what is owed back and when.
Before stimulation, we confirm the patient's fertility benefit, lifetime and cycle maximums, diagnosis requirements, and whether their plan follows a state mandate. Patients get a clear split of covered and self-pay costs before the first injection.
A coder compares the record with the plan's infertility definition and test requirements before the authorization request goes out, and flags missing results back to your team.
We work fertility denials by reason: correcting patient attribution for partner services, fixing storage units and periods, and appealing coverage denials with the plan's own criteria and the patient's records. Across all specialties, 79% of the denials Qualigenix works are overturned.
We compare final self-pay bills with the Good Faith Estimates given to patients and flag variances near the $400 dispute threshold before the bill goes out. Qualigenix holds a 98.6% compliance and audit pass rate.
A 3-provider podiatry group with roughly 60% Medicare payer mix carried $412,000 in A/R, 38% of it past 120 days. Routine foot care claims (11720, 11721, 11055–11057) had stalled on inconsistent Q7/Q8/Q9 modifiers and class-finding documentation, so payers held or partially paid and nobody worked the remainder. Medicare crossover to secondaries was not being posted, and small patient balances were written off.
We ran a full A/R aging segmentation, worked claims by payer and denial reason rather than by date, rebilled the stalled routine-care claims with corrected modifiers, and reactivated secondary and crossover billing.
A solo podiatrist coding 320 encounters a month was stuck at 82% first-pass acceptance. Routine foot care went out without the systemic-condition diagnosis pairing and class findings Medicare requires, so it read as non-covered. Wound debridement was coded to the wrong depth (11042 for skin and subcutaneous where the note supported 11043 for muscle and fascia). Same-day E/M with a procedure went out without modifier 25 and got bundled.
We rebuilt the coding workflow: diagnosis-to-CPT pairing rules for at-risk foot care, correct Q-modifier logic, depth-based debridement coding tied to the operative note, and disciplined use of modifiers 25 and 59/XS.
A 2-location podiatry practice sat at a 19% denial rate, mostly Medicare routine-foot-care and nail-debridement rejections. The denials clustered in three buckets: medical-necessity rejections on routine foot care (missing qualifying diagnosis and class findings), frequency-edit denials on nail debridement billed inside the 60-day window, and missing Q modifiers that flagged services as non-covered.
We built a front-end denial-prevention layer, checking eligibility and coverage against payer LCDs before claims went out, plus a structured appeal workflow with documentation templates mapped to each denial reason.
Qualigenix codes each step of fertility care, from the first workup to embryo storage.
Estradiol (82670), FSH (83001) and AMH (82166) for ovarian reserve; hysterosalpingography billed as the procedure (58340) and the imaging (74740); and saline infusion sonohysterography (76831).
Qualigenix keeps fertility billing compliant by issuing Good Faith Estimates to self-pay patients and matching final bills to them, applying each plan's own infertility definition before billing treatment as covered, keeping excluded services off covered claims, and billing partner and donor services under the correct patient.

IVF is not a Medicare benefit, so CMS publishes no billing-error data for fertility care. These are Qualigenix's own results across all clients.
Qualigenix charges a percentage of the collections we bring in, so our fee moves with your revenue. The percentage depends on your cycle volume, payer and self-pay mix, and the services you hand over, and we set it after a call with your team.
We bill to each payer's contract: S-code case rates such as S4011 or S4015 where the payer pays a case rate, itemized CPT where it doesn't, and never both for the same cycle.
Yes. We prepare Good Faith Estimates for uninsured and self-pay patients and compare the final bill with the estimate, flagging any variance near the $400 dispute threshold.
Yes. We work outstanding fertility claims by payer and denial reason, correct attribution and authorization errors, and appeal coverage denials. Across all Qualigenix clients, days in A/R have dropped from 54 to 36.
Yes. We identify which benefit manager or carrier holds each patient's fertility benefit, submit authorizations in that program's format, and bill inside the authorized cycle.
We verify the fertility benefit before stimulation starts, split each planned service into covered and self-pay, bill the covered portion to the payer, and price the rest up front with a Good Faith Estimate.
Yes. Qualigenix is system-agnostic and works in the IVF practice management and EMR systems clinics already use, across 133 EMR/EHR platforms.